Q: Do I have to compile Mesa with –enable-dri3?
A: It's not required and you may want not to have it. DRI2 works but it is like 3% slower.
Q: I have an Intel card, can I test nine/st?
A: You'll need to compile the i915g driver (for older Intel cards) or ilo. Don't expect it to be flawless on these drivers.
Q: Why do I need to compile Mesa first?
A: Mesa installs headers which are used by wine compilation.
Q: Why do applications report a Geforce GTX 680, but I have a different card?
A: Update Mesa. Upstream now has support for Windows-like card names.